Literature summary for 2.5.1.54 extracted from

Stuart, F.; Hunter, I.S.
Purification and characterisation of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Streptomyces rimosus (1993), Biochim. Biophys. Acta, 1161, 209-215.

Search for more literature for 2.5.1.54

Inhibitors

Inhibitors	Comment	Organism	Structure
Trp	Trp-sensitive isozyme	Streptomyces rimosus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0026	-	D-erythrose 4-phosphate	pH 7.0, 37°C	Streptomyces rimosus
0.0067	-	phosphoenolpyruvate	pH 7.0, 37°C	Streptomyces rimosus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
59000	-	2 * 59000, SDS-PAGE	Streptomyces rimosus
120000	-	gel filtration	Streptomyces rimosus

Organism

Organism	UniProt	Comment	Textmining
Streptomyces rimosus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
2700fold	Streptomyces rimosus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
7.8	-	purified enzyme	Streptomyces rimosus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O	-	Streptomyces rimosus	2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate	-	?

Subunits

Subunits	Comment	Organism
dimer	2 * 59000, SDS-PAGE	Streptomyces rimosus

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Streptomyces rimosus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7	-	-	Streptomyces rimosus

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Release 2023.1 (January 2023)