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Literature summary for 2.5.1.47 extracted from

  • Chattopadhyay, A.; Meier, M.; Ivaninskii, S.; Burkhard, P.; Speroni, F.; Campanini, B.; Bettati, S.; Mozzarelli, A.; Rabeh, W.M.; Li, L.; Cook, P.F.
    Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes (2007), Biochemistry, 46, 8315-8330.
    View publication on PubMed
Search for more literature for 2.5.1.47

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging-drop vapor diffusion method, structure of O-acetylserine sulfhydrylase B solved to 2.3 A Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information the B-isozyme has a an about 10fold lower Km for O-acetyl-L-serine than the A-isoenzyme Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium P0A1E3
-
-
Salmonella enterica subsp. enterica serovar Typhimurium P29848
-
-

Source Tissue

Source Tissue Comment Organism Textmining
culture condition:aerobically-grown cell A-isozyme expressed under aerobic and the B-isozyme expressed under anaerobic conditions Salmonella enterica subsp. enterica serovar Typhimurium
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culture condition:anaerobically-grown cell A-isozyme expressed under aerobic and the B-isozyme expressed under anaerobic conditions Salmonella enterica subsp. enterica serovar Typhimurium
-

Synonyms

Synonyms Comment Organism
CSase A
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 Salmonella enterica subsp. enterica serovar Typhimurium
CSase B
-
 Salmonella enterica subsp. enterica serovar Typhimurium
O-acetylserine (thiol)-lyase A
-
 Salmonella enterica subsp. enterica serovar Typhimurium
O-acetylserine (thiol)-lyase B
-
 Salmonella enterica subsp. enterica serovar Typhimurium
O-acetylserine sulfhydrylase
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 Salmonella enterica subsp. enterica serovar Typhimurium
O-acetylserine sulfhydrylase A
-
 Salmonella enterica subsp. enterica serovar Typhimurium
O-acetylserine sulfhydrylase B
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information the B-isozyme has a turnover number 12.5fold higher than the A-isozyme Salmonella enterica subsp. enterica serovar Typhimurium