Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
single gene | - |
Saccharomyces cerevisiae | - |
single gene | - |
Synonyms | Comment | Organism |
---|---|---|
deoxyhypusine synthase | - |
Mus musculus |
deoxyhypusine synthase | - |
Saccharomyces cerevisiae |
DHS | - |
Mus musculus |
DHS | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
malfunction | a haploid Saccharomyces cerevisiae strain with disruption of the DHS gene is not viable, and can be rescued by a plasmid encoding the wild type DHS. When examined under the microscope, a non-viable DHS-disrupted ascus from a tetrad dissection grows several generations to a colony of 100-200 enlarged cells before growth arrest | Saccharomyces cerevisiae |
malfunction | Dhps+/- mice appear normal and do not show any growth defects or phenotypes. When the heterozygous male and female mice are crossed, no pups are born with the genotype of Dhps-/- homozygous deletion, indicating that DHS is vital for growth and survival | Mus musculus |