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Literature summary for 2.5.1.45 extracted from
- Cloning and expression of homospermidine synthase from Senecio vulgaris: a revision (2000), Phytochemistry, 55, 305-309.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Senecio vulgaris |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 40740 | - |
4 * 40740, calculation from sequence of cDNA | Senecio vulgaris |
| 45000 | - |
4 * 45000, SDS-PAGE | Senecio vulgaris |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| putrescine + spermine | Senecio vulgaris | the plant homospermidine synthase is essentially dependent on spermidine as aminobutyl donor and is unable to synthesize homospermidine from two molecules of putrescine | sym-homospermine + propane-1,3-diamine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Senecio vulgaris | Q9M4B0 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| root | - |
Senecio vulgaris | - |
| tissue culture | - |
Senecio vulgaris | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| putrescine + spermidine | the plant homospermidine synthase is essentially dependent on spermidine as aminobutyl donor and is unable to synthesize homospermidine from two molecules of putrescine | Senecio vulgaris | N-(4-aminobutyl)butane-1,4-diamine + propane-1,3-diamine | - |
? | |
| putrescine + spermine | the plant homospermidine synthase is essentially dependent on spermidine as aminobutyl donor and is unable to synthesize homospermidine from two molecules of putrescine | Senecio vulgaris | sym-homospermine + propane-1,3-diamine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 45000, SDS-PAGE | Senecio vulgaris |
| tetramer | 4 * 40740, calculation from sequence of cDNA | Senecio vulgaris |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Senecio vulgaris | |
| NADH | - |
Senecio vulgaris | |
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