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Literature summary for 2.5.1.43 extracted from

  • Lee, S.; Kim, Y.S.; Jeon, U.S.; Kim, Y.K.; Schjoerring, J.K.; An, G.
    Activation of Rice nicotianamine synthase 2 (OsNAS2) enhances iron availability for biofortification (2012), Mol. Cells, 33, 269-275.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expression of nicotianamine synthase in Oryza sativa seeds under the control of the maize ubiquitin promoter Oryza sativa

Protein Variants

Protein Variants Comment Organism
additional information generation of transgenic Oryza sativa plants by expression of iron-inducible nicotianamine synthase for increasing the content of bioavailable iron in seeds. Enhanced expression leads to higher tolerance of Fe deficiency and better growth under elevated pH, the iron content is increased 3fold by activating the recombinant NAS, phenotypes, overview Oryza sativa

Organism

Organism UniProt Comment Textmining
Oryza sativa
-
 gene OsNAS2
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Oryza sativa
-
seedling expression of Fe homeostasis-related genes in wild-type and transgenic overexpressing seedlings, overview Oryza sativa
-
shoot
-
 Oryza sativa
-

Synonyms

Synonyms Comment Organism
nicotianamine synthase 2
-
 Oryza sativa
OsNAS2
-
 Oryza sativa

Expression

Organism Comment Expression
Oryza sativa OsNAS2 is iron deficiency-inducible, while Zn-, Cu-, and Mn-deficiencies have no effect on the gene expression up

General Information

General Information Comment Organism
additional information activation of iron deficiency-inducible OsNAS2 results in a 3.0fold rise in Fe content in mature seeds. OsNAS2 ectopic expression also increases the iron content. Enhanced expression leads to higher tolerance of Fe deficiency and better growth under elevated pH. Mice fed with OsNAS2-D1 seeds recover more rapidly from anemia, indicating that bioavailable Fe contents are improved by this increase in OsNAS2 expression, phenotypes, overview Oryza sativa