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Literature summary for 2.5.1.34 extracted from

  • Steffan, N.; Li, S.M.
    Increasing structure diversity of prenylated diketopiperazine derivatives by using a 4-dimethylallyltryptophan synthase (2009), Arch. Microbiol., 191, 461-466.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.009
-
L-tryptophan
-
Aspergillus fumigatus
0.14
-
cyclo-L-tryptophan-L-leucine
-
Aspergillus fumigatus
0.326
-
cyclo-L-tryptophan-L-tryptophan
-
Aspergillus fumigatus
0.354
-
cyclo-L-tryptophan-L-tyrosine
-
Aspergillus fumigatus
0.439
-
cyclo-L-tryptophan-glycine
-
Aspergillus fumigatus
0.536
-
cyclo-L-tryptophan-L-proline
-
Aspergillus fumigatus

Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dimethylallyl diphosphate + cyclo-L-tryptophan-glycine
-
Aspergillus fumigatus diphosphate + cyclo-L-4-dimethylallyltryptophan-glycine
-
?
dimethylallyl diphosphate + cyclo-L-tryptophan-L-leucine
-
Aspergillus fumigatus diphosphate + cyclo-L-4-dimethylallyltryptophan-L-leucine
-
?
dimethylallyl diphosphate + cyclo-L-tryptophan-L-proline
-
Aspergillus fumigatus diphosphate + cyclo-L-4-dimethylallyltryptophan-L-proline
-
?
dimethylallyl diphosphate + cyclo-L-tryptophan-L-tryptophan
-
Aspergillus fumigatus diphosphate + cyclo-L-4-dimethylallyltryptophan-L-tryptophan
-
?
dimethylallyl diphosphate + cyclo-L-tryptophan-L-tyrosine
-
Aspergillus fumigatus diphosphate + cyclo-L-4-dimethylallyltryptophan-L-tyrosine
-
?
dimethylallyl diphosphate + L-tryptophan
-
Aspergillus fumigatus diphosphate + 4-dimethylallyl-L-tryptophan
-
?

Synonyms

Synonyms Comment Organism
dimethylallyltryptophan synthase
-
Aspergillus fumigatus
FgaPT2
-
Aspergillus fumigatus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.00106
-
cyclo-L-tryptophan-glycine
-
Aspergillus fumigatus
0.00113
-
cyclo-L-tryptophan-L-proline
-
Aspergillus fumigatus
0.0017
-
cyclo-L-tryptophan-L-tyrosine
-
Aspergillus fumigatus
0.0017
-
cyclo-L-tryptophan-L-leucine
-
Aspergillus fumigatus
0.0021
-
cyclo-L-tryptophan-L-tryptophan
-
Aspergillus fumigatus
0.26
-
L-tryptophan
-
Aspergillus fumigatus

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
21
-
cyclo-L-tryptophan-L-proline
-
Aspergillus fumigatus
24
-
cyclo-L-tryptophan-glycine
-
Aspergillus fumigatus
39.33
-
L-tryptophan
-
Aspergillus fumigatus
48
-
cyclo-L-tryptophan-L-tyrosine
-
Aspergillus fumigatus
66.5
-
cyclo-L-tryptophan-L-tryptophan
-
Aspergillus fumigatus
122
-
cyclo-L-tryptophan-L-leucine
-
Aspergillus fumigatus