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Literature summary for 2.5.1.31 extracted from

  • Rush, J.; Matveev, S.; Guan, Z.; Raetz, C.; Waechter, C.
    Expression of functional bacterial undecaprenyl pyrophosphate synthase in the yeast rer2DELTA mutant and CHO cells (2010), Glycobiology, 20, 1585-1593.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene uppS, expression of GFP-tagged UPPS in CHO cell endoplasmic reticulum, expression in Saccharomyces cerevisiae microsomes, ability of the Escherichia coli undecaprenyl pyrophosphate synthase to complement the loss of the yeast cis isoprenyltransferase in the rer2DELTA mutant Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
Escherichia coli 5783
-
membrane
-
Escherichia coli 16020
-
microsome
-
Escherichia coli
-
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
gene uppS
-

Synonyms

Synonyms Comment Organism
undecaprenyl pyrophosphate synthase
-
Escherichia coli
UPPs
-
Escherichia coli

General Information

General Information Comment Organism
physiological function expression of UPPS in the yeast mutant rer2DELTA, lacking undecaprenyl diphosphate synthase, complements the growth and the hypoglycosylation of carboxypeptidase Y defects. Mutant cells expressing UPPS synthesize dolichyl phosphate of chain length C55 and utilize it to form Man-P-(55)Dol in vitro and in vivo, and they synthesize N-linked glycoprotein Escherichia coli