Protein Variants | Comment | Organism |
---|---|---|
F77G | C30-prenyl diphosphate is the main long product | Sulfolobus acidocaldarius |
F77G/H114A | C45-prenyl diphosphate is the main long product | Sulfolobus acidocaldarius |
F77G/H114G | although its activity is approximately 2-5% of the wild-type, this double-mutated enzyme exhibits a detectable activity and a thermostability to resist 15 h of heat treatment at 55°C. C50-prenyl diphosphate is the main long product | Sulfolobus acidocaldarius |
H114A | C30-prenyl diphosphate is the main long product | Sulfolobus acidocaldarius |
H114G | C40-prenyl diphosphate is the main long product | Sulfolobus acidocaldarius |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sulfolobus acidocaldarius | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate | the wild-type enzyme produces mostly 87% geranylgeranyl diphosphate. The mutant enzymes F77G, F77G/H114A, F77G/H114G, H114A, and H114G give C30, C45, C50, C30 and C40 as the main long product, respectively | Sulfolobus acidocaldarius | diphosphate + geranylgeranyl diphosphate | - |
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Synonyms | Comment | Organism |
---|---|---|
GGPS | - |
Sulfolobus acidocaldarius |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
55 | - |
assay at | Sulfolobus acidocaldarius |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.8 | - |
assay at | Sulfolobus acidocaldarius |