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Literature summary for 2.5.1.26 extracted from

  • Zomer, A.W.M.; Opperdoes, F.R.; van den Bosch, H.
    Alkyl dihydroxyacetone phosphate synthase in glycosomes of Trypanosoma brucei (1995), Biochim. Biophys. Acta, 1257, 167-173.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Trypanosoma brucei

Inhibitors

Inhibitors Comment Organism Structure
2-oxo-3-(phosphonooxy)propyl hexadecanoate inhibitory above 0.1 mM Trypanosoma brucei
hexadecanol inhibitory above 0.3 mM Trypanosoma brucei
NaCl 50% inhibition at 0.6 M Trypanosoma brucei

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.042
-
hexadecanol
-
Trypanosoma brucei
0.1
-
Palmitoyldihydroxyacetone phosphate
-
Trypanosoma brucei

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome type-1 peroxisomal targeting signal Trypanosoma brucei 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68900
-
x * 68900, deduced from gene sequence Trypanosoma brucei

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei O97157
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyldihydroxyacetone phosphate + octadecanol
-
Trypanosoma brucei palmitate + 1-O-octadecyldihydroxyacetone phosphate
-
?
stearoyldihydroxyacetone phosphate + hexadecanol
-
Trypanosoma brucei stearate + 1-O-hexadecyldihydroxyacetone phosphate
-
?

Subunits

Subunits Comment Organism
? x * 68900, deduced from gene sequence Trypanosoma brucei