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BRENDA support

Literature summary for 2.5.1.21 extracted from

  • Brusselmans, K.; Timmermans, L.; Van de Sande, T.; Van Veldhoven, P.P.; Guan, G.; Shechter, I.; Claessens, F.; Verhoeven, G.; Swinnen, J.V.
    Squalene synthase, a determinant of raft-associated cholesterol and modulator of cancer cell proliferation (2007), J. Biol. Chem., 282, 18777-18785.
    View publication on PubMed

Application

Application Comment Organism
medicine potential target for antineoplastic intervention Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
zaragozic acid A 0.04 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
prostate cancer cell line
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
farnesyl diphosphate + farnesyl diphosphate
-
Homo sapiens diphosphate + presqualene diphosphate
-
?

Synonyms

Synonyms Comment Organism
SQS
-
Homo sapiens