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Literature summary for 2.5.1.18 extracted from
- The characterization of cytosolic glutathione transferase from four species of sea turtles: Loggerhead (Caretta caretta), green (Chelonia mydas), olive ridley (Lepidochelys olivacea), and hawksbill (Eretmochelys imbricata) (2009), Comp. Biochem. Physiol. C, 150, 279-284.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.122 | - |
glutathione | pH 7.2, 25°C | Eretmochelys imbricata |  |
| 0.163 | - |
glutathione | pH 7.2, 25°C | Chelonia mydas | |
| 0.172 | - |
glutathione | pH 7.2, 25°C | Caretta caretta | |
| 0.225 | - |
glutathione | pH 7.2, 25°C | Lepidochelys olivacea | |
| 0.269 | - |
1-chloro-2,4-dinitrobenzene | pH 7.2, 25°C | Caretta caretta | |
| 0.373 | - |
1-chloro-2,4-dinitrobenzene | pH 7.2, 25°C | Lepidochelys olivacea | |
| 0.455 | - |
1-chloro-2,4-dinitrobenzene | pH 7.2, 25°C | Eretmochelys imbricata | |
| 0.547 | - |
1-chloro-2,4-dinitrobenzene | pH 7.2, 25°C | Chelonia mydas | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Caretta caretta | 5829 | - |
| cytosol | - |
Chelonia mydas | 5829 | - |
| cytosol | - |
Lepidochelys olivacea | 5829 | - |
| cytosol | - |
Eretmochelys imbricata | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caretta caretta | - |
- |
- |
| Chelonia mydas | - |
- |
- |
| Eretmochelys imbricata | - |
- |
- |
| Lepidochelys olivacea | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Caretta caretta | - |
| liver | - |
Chelonia mydas | - |
| liver | - |
Lepidochelys olivacea | - |
| liver | - |
Eretmochelys imbricata | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrobenzyl chloride + glutathione | - |
Caretta caretta | S-(4-nitrobenzyl)glutathione + HCl | - |
? | |
| 4-nitrobenzyl chloride + glutathione | - |
Chelonia mydas | S-(4-nitrobenzyl)glutathione + HCl | - |
? | |
| 4-nitrobenzyl chloride + glutathione | - |
Lepidochelys olivacea | S-(4-nitrobenzyl)glutathione + HCl | - |
? | |
| 4-nitrobenzyl chloride + glutathione | - |
Eretmochelys imbricata | S-(4-nitrobenzyl)glutathione + HCl | - |
? | |
| DELTA5-androstene-3,17-dione + glutathione | - |
Caretta caretta | ? | - |
? | |
| DELTA5-androstene-3,17-dione + glutathione | - |
Chelonia mydas | ? | - |
? | |
| DELTA5-androstene-3,17-dione + glutathione | - |
Lepidochelys olivacea | ? | - |
? | |
| DELTA5-androstene-3,17-dione + glutathione | - |
Eretmochelys imbricata | ? | - |
? | |
| ethacrynic acid + glutathione | - |
Caretta caretta | ? | - |
? | |
| ethacrynic acid + glutathione | - |
Chelonia mydas | ? | - |
? | |
| ethacrynic acid + glutathione | - |
Lepidochelys olivacea | ? | - |
? | |
| ethacrynic acid + glutathione | - |
Eretmochelys imbricata | ? | - |
? | |
| glutathione + 1-chloro-2,4-dinitrobenzene | - |
Caretta caretta | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? | |
| glutathione + 1-chloro-2,4-dinitrobenzene | - |
Chelonia mydas | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? | |
| glutathione + 1-chloro-2,4-dinitrobenzene | - |
Lepidochelys olivacea | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? | |
| glutathione + 1-chloro-2,4-dinitrobenzene | - |
Eretmochelys imbricata | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Caretta caretta |
| 25 | - |
assay at | Chelonia mydas |
| 25 | - |
assay at | Lepidochelys olivacea |
| 25 | - |
assay at | Eretmochelys imbricata |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.2 | - |
assay at | Caretta caretta |
| 7.2 | - |
assay at | Chelonia mydas |
| 7.2 | - |
assay at | Lepidochelys olivacea |
| 7.2 | - |
assay at | Eretmochelys imbricata |
kcat/KM [mM/s]
| kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 2.02 | - |
1-chloro-2,4-dinitrobenzene | pH 7.2, 25°C | Eretmochelys imbricata | |
| 3.24 | - |
1-chloro-2,4-dinitrobenzene | pH 7.2, 25°C | Chelonia mydas | |
| 4.16 | - |
1-chloro-2,4-dinitrobenzene | pH 7.2, 25°C | Lepidochelys olivacea | |
| 4.68 | - |
glutathione | pH 7.2, 25°C | Lepidochelys olivacea | |
| 5.72 | - |
1-chloro-2,4-dinitrobenzene | pH 7.2, 25°C | Caretta caretta | |
| 6.16 | - |
glutathione | pH 7.2, 25°C | Eretmochelys imbricata | |
| 7.52 | - |
glutathione | pH 7.2, 25°C | Caretta caretta | |
| 7.7 | - |
glutathione | pH 7.2, 25°C | Chelonia mydas | |
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