Protein Variants | Comment | Organism |
---|---|---|
D141N | site-directed mutagenesis of isozyme GST T1-1, the mutant enzyme behaves similarly to the wild-type enzyme, in terms of expression level and specific activity. The mutant activity with ethidium bromide is highly reduced compared to the wild-type enzyme | Homo sapiens |
E173K | site-directed mutagenesis of isozyme GST T1-1, the mutant shows reduced expression levels and enzyme activity with all substrates compared to the wild-type enzyme. The mutant is not active with ethidium bromide | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
S-hexyl glutathione | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P30711 | isozyme GST T1-1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + 1,2-epoxy-3-(p-nitrophenoxy)propane | - |
Homo sapiens | ? | - |
? | |
glutathione + 4-nitrobenzyl chloride | - |
Homo sapiens | S-(4-nitrobenzyl)glutathione + HCl | - |
? | |
glutathione + ethylene diiodide | - |
Homo sapiens | ? | - |
? | |
additional information | GST T1-1 displays both glutathione transferase and glutathione peroxidase enzyme activities, the latter with CuOOH | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glutathione transferase T1-1 | - |
Homo sapiens |
GST T1-1 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Homo sapiens |