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Literature summary for 2.5.1.18 extracted from

  • Schuller, D.J.; Liu, Q.; Kriksunov, I.A.; Campbell, A.M.; Barrett, J.; Brophy, P.M.; Hao, Q.
    Crystal structure of a new class of glutathione transferase from the model human hookworm nematode Heligmosomoides polygyrus (2005), Proteins, 61, 1024-1031.
    View publication on PubMed

Application

Application Comment Organism
drug development the enzyme is a target for structure-based drug/inhibitor design Heligmosomoides polygyrus

Crystallization (Commentary)

Crystallization (Comment) Organism
isozyme GST Nu2-2, X-ray diffraction structure determination and analysis at 1.71 A resolution, molecular replacement method Heligmosomoides polygyrus

Organism

Organism UniProt Comment Textmining
Heligmosomoides polygyrus
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human hookworm, isozyme GST Nu2-2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme ligand binding site structure, overview Heligmosomoides polygyrus ?
-
?

Subunits

Subunits Comment Organism
dimer subunit-subunit interactions of isozyme GST Nu2-2, crystal structure analysis, overview Heligmosomoides polygyrus

Synonyms

Synonyms Comment Organism
GST
-
Heligmosomoides polygyrus