Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benastatin A | IC50: 0.00041 mM | Lactuca sativa | |
Ethacrynic acid | 0.00028 mM | Lactuca sativa | |
S-(2,4-dinitrophenyl)glutathione | IC50: 0.0034 mM | Lactuca sativa | |
S-hexyl-GSH | IC50: 0.0152 mM | Lactuca sativa | |
S-methyl-GSH | IC50: 0.0123 mM | Lactuca sativa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
23000 | - |
2 * 23000, SDS-PAGE | Lactuca sativa |
48000 | - |
gel filtration | Lactuca sativa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lactuca sativa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Lactuca sativa |
Source Tissue | Comment | Organism | Textmining |
---|
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
4.03 | - |
- |
Lactuca sativa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,2-epoxy-3-(p-nitrophenoxy)propane + glutathione | - |
Lactuca sativa | ? | - |
? | |
1-chloro-2,3-dinitrobenzene + glutathione | - |
Lactuca sativa | S-(2,3-dinitrophenyl)glutathione + HCl | - |
? | |
ethacrynic acid + glutathione | - |
Lactuca sativa | ? | - |
? | |
additional information | the enzyme also exhibits glutathione peroxidase activity towards cumene hydroperoxide | Lactuca sativa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 23000, SDS-PAGE | Lactuca sativa |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
10 min, stable up to | Lactuca sativa |
50 | - |
10 min, about 40% loss of activity | Lactuca sativa |
60 | - |
10 min, about 75% loss of activity | Lactuca sativa |
65 | - |
10 min, about 90% loss of activity | Lactuca sativa |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00041 | - |
IC50: 0.00041 mM | Lactuca sativa | benastatin A | |
0.0034 | - |
IC50: 0.0034 mM | Lactuca sativa | S-(2,4-dinitrophenyl)glutathione | |
0.0123 | - |
IC50: 0.0123 mM | Lactuca sativa | S-methyl-GSH | |
0.0152 | - |
IC50: 0.0152 mM | Lactuca sativa | S-hexyl-GSH |