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Literature summary for 2.5.1.18 extracted from

  • Reddy, C.C.; Li, N.Q.; Tu, C.P.D.
    Identification of a new glutathione S-transferase from rat liver cytosol (1984), Biochem. Biophys. Res. Commun., 121, 1014-1020.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Rattus norvegicus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24400
-
2 * 24400, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.12
-
with cumene hydroperoxide as substrate Rattus norvegicus
0.18
-
with 4-nitrophenyl acetate as substrate Rattus norvegicus
0.34
-
with ethacrynic acid as substrate Rattus norvegicus
0.4
-
with 1,2-epoxy-3-(4-nitrophenoxy)propane as substrate Rattus norvegicus
1.8
-
with 1-chloro-2,4-dinitrobenzene as substrate Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + 1,2-dichloro-4-nitrobenzene
-
Rattus norvegicus ?
-
?
glutathione + 1,2-epoxy-3-(4-nitrophenoxy)propane
-
Rattus norvegicus ?
-
?
glutathione + 1-chloro-2,4-dinitrobenzene
-
Rattus norvegicus S-2,4-dinitrophenylglutathione + HCl
-
?
glutathione + 4-nitrobenzyl chloride
-
Rattus norvegicus ?
-
?
glutathione + 4-nitrophenyl acetate
-
Rattus norvegicus ?
-
?
glutathione + 4-nitropyridine
-
Rattus norvegicus ?
-
?
glutathione + androst-5-ene-3,17-dione
-
Rattus norvegicus ?
-
?
glutathione + bromosulfophthalein
-
Rattus norvegicus ?
-
?
glutathione + cumene hydroperoxide
-
Rattus norvegicus ?
-
?
glutathione + ethacrynic acid
-
Rattus norvegicus ?
-
?
glutathione + linoleic acid hydroperoxide
-
Rattus norvegicus ?
-
?
glutathione + tert-butyl hydroperoxide
-
Rattus norvegicus ?
-
?
additional information specificity Rattus norvegicus ?
-
?
RX + glutathione RX: R: aliphatic, aromatic or heterocyclic, X: sulfate, nitrite or halide, enzyme also catalyzes: the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrite, certain isomerization reactions and disulfide interchange Rattus norvegicus HX + R-S-glutathione
-
?

Subunits

Subunits Comment Organism
dimer 2 * 24400, SDS-PAGE Rattus norvegicus