Any feedback?
Literature summary for 2.5.1.18 extracted from
- Glutathione transferase (human placenta) (1981), Methods Enzymol., 77, 231-235.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Homo sapiens | |
| 0.5 | - |
glutathione | - |
Homo sapiens |  |
| 2.1 | - |
1-chloro-2,4-dinitrobenzene | - |
Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 47000 | - |
- |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.01 | - |
with trans-4-phenyl-3-buten-2-one as substrate | Homo sapiens |
| 0.03 | - |
with cumene hydroperoxide as substrate | Homo sapiens |
| 0.07 | - |
with styrene oxide as substrate | Homo sapiens |
| 0.11 | - |
with 3,4-dichloro-1-nitrobenzene as substrate | Homo sapiens |
| 0.37 | - |
with 1,2-epoxy-3-(4-nitrophenoxy)propane as substrate | Homo sapiens |
| 105 | - |
with 1-chloro-2,4-dinitrobenzene as substrate | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione + 1-chloro-2,4-dinitrobenzene | - |
Homo sapiens | S-2,4-dinitrophenylglutathione + HCl | - |
? | |
| glutathione + 3,4-dichloro-1-nitrobenzene | - |
Homo sapiens | ? | - |
? | |
| glutathione + cumene hydroperoxide | - |
Homo sapiens | ? | - |
? | |
| glutathione + styrene oxide | - |
Homo sapiens | ? | - |
? | |
| glutathione + trans-4-phenyl-3-buten-2-one | - |
Homo sapiens | ? | - |
? | |
| additional information | no substrates: sulfobromophthalein and hydrogen peroxide | Homo sapiens | ? | - |
? | |
| RX + glutathione | RX: R: aliphatic, aromatic or heterocyclic, X: sulfate, nitrite or halide, enzyme also catalyzes: the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrite, certain isomerization reactions and disulfide interchange | Homo sapiens | HX + R-S-glutathione | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
