Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 (lambdaDE3) Rosetta Oxford cells | Plasmodium falciparum |
Crystallization (Comment) | Organism |
---|---|
in complex with S-methyl-5'-thioadenosine and putrescine or inhibitors, hanging drop vapor diffusion method, using 0.1 M MES buffer pH 5.6, 0.1 M ammonium sulfate, 27% (w/v) PEG 3350 | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-methylaniline | - |
Plasmodium falciparum | |
benzimidazol-(2-yl)pentan-1-amine | - |
Plasmodium falciparum | |
S-adenosyl-1,8-diamino-3-thio-octane | - |
Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl 3-(methylthio)propylamine + putrescine | Plasmodium falciparum | - |
S-methyl-5'-thioadenosine + spermidine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | Q8II73 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-affinity column chromatography | Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl 3-(methylthio)propylamine + putrescine | - |
Plasmodium falciparum | S-methyl-5'-thioadenosine + spermidine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SPDS | - |
Plasmodium falciparum |