Literature summary for 2.5.1.15 extracted from

Haasum, Y.; Strom, K.; Wehelie, R.; Luna, V.; Roberts, M.C.; Maskell, J.P.; Hall, L.M.C.; Swedberg, G.
Amino acid repetitions in the dihydropteroate synthase of Streptococcus pneumoniae lead to sulfonamide resistance with limited effects on substrate Km (2001), Antimicrob. Agents Chemother., 45, 805-809.

Search for more literature for 2.5.1.15

Cloned(Commentary)

Cloned (Comment)	Organism
expression in different Escherichia coli strains	Streptococcus pneumoniae

Inhibitors

Inhibitors	Comment	Organism	Structure
sulfathiazole	competitive to 4-aminobenzoate	Streptococcus pneumoniae

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
additional information	-	additional information	activity in Streptococcus pneumoniae strains with different repeats of amino acids	Streptococcus pneumoniae

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Streptococcus pneumoniae	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
gel filtration and ion-exchange chromatography	Streptococcus pneumoniae

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
additional information	-	additional information	KI values of sulfathiazole inhibition on Streptococcus pneumoniae strains with different repeats of amino acids	Streptococcus pneumoniae

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Release 2023.1 (January 2023)