Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-phospho-L-serine + [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH | Mycobacterium tuberculosis | the specificity of the enzyme for the physiological sulfide equivalent [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH is more than 3 orders of magnitude greater than that for bisulfide | [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
nickel affinity column chromatography | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-acetyl-L-serine + [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH | the specificity of the enzyme for its amino acid substrate is more than 500fold greater for O-phospho-L-serine than for O-acetyl-L-serine | Mycobacterium tuberculosis | ? | - |
? | |
O-phospho-L-serine + [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH | the specificity of the enzyme for the physiological sulfide equivalent [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH is more than 3 orders of magnitude greater than that for bisulfide | Mycobacterium tuberculosis | [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CysM | - |
Mycobacterium tuberculosis |
Cysteine synthase | - |
Mycobacterium tuberculosis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Mycobacterium tuberculosis |