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Literature summary for 2.5.1.1 extracted from

  • Nagaki, M.; Musashi, T.; Hirano, Y.; Tanaka, H.; Ichita, J.; Maki, Y.; Koyama, T.
    Substrate specificities of farnesyl diphosphate synthases of Bacillus stearothermophilus and porcine liver with allylic substrate homologs having vinyl or ethynyl group (2009), J. Mol. Catal. B, 59, 163-167.
No PubMed abstract available

Protein Variants

Protein Variants Comment Organism
Y81D contrary to wild-type, reaction of (Z)-ethynyldimethylallyl diphosphate plus isopentenyl diphosphate yields a mixture of products ethynylgeranyl, ethynylfarnesyl, and ethynylgeranylgeranyl diphosphates Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
bifunctional geranyl diphosphate synthase EC 2.5.1.1 and farnesyl diphosphate synthase EC 2.5.1.10
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(Z)-ethynyldimethylallyl diphosphate + isopentenyl diphosphate
-
Sus scrofa (Z)-ethynylfarnesyl diphosphate + diphosphate sole product with wild-type, yield is 21.9% Z-ethynylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate ?
vinyldimethylallyl diphosphate + isopentenyl diphosphate
-
Sus scrofa vinylgeranyl diphosphate + vinylfarnesyl diphosphate + diphosphate 14.3% vinylgeranyl diphosphate plus 23.3% vinylfarnesyl diphosphate, compared with 100% for the reaction of dimethylallyl diphosphate with isopentenyl diphosphate ?