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Literature summary for 2.4.2.58 extracted from

  • Ogawa-Ohnishi, M.; Matsushita, W.; Matsubayashi, Y.
    Identification of three hydroxyproline O-arabinosyltransferases in Arabidopsis thaliana (2013), Nat. Chem. Biol., 9, 726-730.
    View publication on PubMed
Search for more literature for 2.4.2.58

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus Golgi-localized transmembrane protein Arabidopsis thaliana 5794
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-beta-L-arabinofuranose + [protein]-trans-4-hydroxy-L-proline Arabidopsis thaliana the enzyme catalyses the O-arabinosylation of hydroxyprolines in hydroxyproline-rich glycoproteins. The enzyme acts on the first hydroxyproline in the motif Val-hydroxyPro-hydroxyPro-Ser UDP + [protein]-trans-4-(beta-L-arabinofuranosyl)oxy-L-proline
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Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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Purification (Commentary)

Purification (Comment) Organism
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 Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-beta-L-arabinofuranose + [protein]-trans-4-hydroxy-L-proline the enzyme catalyses the O-arabinosylation of hydroxyprolines in hydroxyproline-rich glycoproteins. The enzyme acts on the first hydroxyproline in the motif Val-hydroxyPro-hydroxyPro-Ser Arabidopsis thaliana UDP + [protein]-trans-4-(beta-L-arabinofuranosyl)oxy-L-proline
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 ?
UDP-beta-L-arabinofuranose + [protein]-trans-4-hydroxy-L-proline trans-4-hydroxy-L-proline i.e. (2S,4R)-4-hydroxyproline i.e. (4R)-4-hydroxy-L-proline Arabidopsis thaliana UDP + [protein]-trans-4-(beta-L-arabinofuranosyl)oxy-L-proline
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 ?

Synonyms

Synonyms Comment Organism
hpat
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 Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction loss-of-function mutations in hydroxyproline O-arabinosyltransferase-encoding genes cause pleiotropic phenotypes that include enhanced hypocotyl elongation, defects in cell wall thickening, early flowering, early senescence and impaired pollen tube growth Arabidopsis thaliana
physiological function essential role of Hyp O-arabinosylation in both vegetative and reproductive growth (hypocotyl elongation, cell wall thickening, flowering, senescence and pollen tube growth) Arabidopsis thaliana