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Literature summary for 2.4.2.55 extracted from
- ArsAB, a novel enzyme from Sporomusa ovata activates phenolic bases for adenosylcobamide biosynthesis (2011), Mol. Microbiol., 81, 952-967.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Sporomusa ovata |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 36650 | - |
1 * 36650 (ArsA) + 1 * 361800 (ArsB), calculated from sequence | Sporomusa ovata |
| 66000 | - |
gel filtration | Sporomusa ovata |
| 361800 | - |
1 * 36650 (ArsA) + 1 * 361800 (ArsB), calculated from sequence | Sporomusa ovata |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| beta-nicotinate D-ribonucleotide + 4-cresol | Sporomusa ovata | the enzyme is involved in the biosynthesis of phenolic cobamides in Sporomusa ovata | nicotinate + 4-methylphenyl 5-phospho-alpha-D-ribofuranoside | - |
? |  |
| beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole | Sporomusa ovata | the enzyme is involved in the biosynthesis of phenolic cobamides in Sporomusa ovata | nicotinate + alpha-ribazole 5'-phosphate | - |
? | |
| beta-nicotinate D-ribonucleotide + phenol | Sporomusa ovata | the enzyme is involved in the biosynthesis of phenolic cobamides in Sporomusa ovata | nicotinate + phenyl 5-phospho-alpha-D-ribofuranoside | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sporomusa ovata | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sporomusa ovata |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.019 | - |
pH 9.0, 37°C | Sporomusa ovata |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| beta-nicotinate D-ribonucleotide + 4-cresol | - |
Sporomusa ovata | nicotinate + 4-methylphenyl 5-phospho-alpha-D-ribofuranoside | - |
? | |
| beta-nicotinate D-ribonucleotide + 4-cresol | the enzyme is involved in the biosynthesis of phenolic cobamides in Sporomusa ovata | Sporomusa ovata | nicotinate + 4-methylphenyl 5-phospho-alpha-D-ribofuranoside | - |
? | |
| beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole | - |
Sporomusa ovata | nicotinate + alpha-ribazole 5'-phosphate | - |
? | |
| beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole | the enzyme is involved in the biosynthesis of phenolic cobamides in Sporomusa ovata | Sporomusa ovata | nicotinate + alpha-ribazole 5'-phosphate | - |
? | |
| beta-nicotinate D-ribonucleotide + phenol | - |
Sporomusa ovata | nicotinate + phenyl 5-phospho-alpha-D-ribofuranoside | - |
? | |
| beta-nicotinate D-ribonucleotide + phenol | the enzyme is involved in the biosynthesis of phenolic cobamides in Sporomusa ovata | Sporomusa ovata | nicotinate + phenyl 5-phospho-alpha-D-ribofuranoside | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterodimer | 1 * 36650 (ArsA) + 1 * 361800 (ArsB), calculated from sequence | Sporomusa ovata |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ArsAB | - |
Sporomusa ovata |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
- |
Sporomusa ovata |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme is involved in the biosynthesis of phenolic cobamides in Sporomusa ovata | Sporomusa ovata |
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Release 2023.1 (January 2023)
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