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Literature summary for 2.4.2.48 extracted from

  • Kawamura, T.; Hirata, A.; Ohno, S.; Nomura, Y.; Nagano, T.; Nameki, N.; Yokogawa, T.; Hori, H.
    Multisite-specific archaeosine tRNA-guanine transglycosylase (ArcTGT) from Thermoplasma acidophilum, a thermo-acidophilic archaeon (2016), Nucleic Acids Res., 44, 1894-1908.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Thermococcus kodakarensis Thermoplasma acidophilum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
guanine15 in tRNA + 7-cyano-7-deazaguanine Thermoplasma acidophilum
-
7-cyano-7-deazaguanine15 in tRNA + guanine
-
?
guanine15 in tRNA + 7-cyano-7-deazaguanine Thermoplasma acidophilum HO-62
-
7-cyano-7-deazaguanine15 in tRNA + guanine
-
?

Organism

Organism UniProt Comment Textmining
Thermoplasma acidophilum
-
-
-
Thermoplasma acidophilum HO-62
-
-
-

Purification (Commentary)

Purification (Comment) Organism
HiTrap Q-Sepharose and HiTrap Heparin-Sepharose column chromatography Thermoplasma acidophilum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
guanine15 in tRNA + 7-cyano-7-deazaguanine
-
Thermoplasma acidophilum 7-cyano-7-deazaguanine15 in tRNA + guanine
-
?
guanine15 in tRNA + 7-cyano-7-deazaguanine
-
Thermoplasma acidophilum HO-62 7-cyano-7-deazaguanine15 in tRNA + guanine
-
?

Synonyms

Synonyms Comment Organism
archaeosine tRNA-guanine transglycosylase
-
Thermoplasma acidophilum
ArcTGT
-
Thermoplasma acidophilum