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Literature summary for 2.4.2.4 extracted from

  • Jeung, H.C.; Che, X.F.; Haraguchi, M.; Zhao, H.Y.; Furukawa, T.; Gotanda, T.; Zheng, C.L.; Tsuneyoshi, K.; Sumizawa, T.; Roh, J.K.; Akiyama, S.
    Protection against DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase (2006), FEBS Lett., 580, 1294-1302.
    View publication on PubMed
Search for more literature for 2.4.2.4

Application

Application Comment Organism
medicine expression of PD-ECGF/TP may play an important role in the progression of solid tumors, and inhibitors of thymidine phosphorylase and analogs of the degradation products of thymidine may suppress the growth of tumors by promoting apoptosis Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in KB cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens expression of PD-ECGF/TP may play an important role in the progression of solid tumors ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P19971
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-

Source Tissue

Source Tissue Comment Organism Textmining
colonic cancer cell patients with PD-ECGF/TP-positive tumors have a poorer prognosis than those with negative tumors Homo sapiens
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esophageal cancer cell patients with PD-ECGF/TP-positive tumors have a poorer prognosis than those with negative tumors Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information expression of PD-ECGF/TP may play an important role in the progression of solid tumors Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase
-
 Homo sapiens
PD-ECGF/TP
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 Homo sapiens