Literature summary for 2.4.2.4 extracted from

Miyadera, K.; Sumizawa, T.; Haraguchi, M.; Yoshida, H.; Konstanty, W.; Yamada, Y.; Akiyama, S.
Role of thymidine phosphorylase activity in the angiogenic effect of platelet derived endothelial cell growth factor/thymidine phosphorylase (1995), Cancer Res., 55, 1687-1690.

Search for more literature for 2.4.2.4

Protein Variants

Protein Variants	Comment	Organism
K115E	no enzyme activity after transfection in COS-7 cells	Homo sapiens
L148R	no enzyme activity after transfection in COS-7 cells	Homo sapiens
R202S	no enzyme activity after transfection in COS-7 cells	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
6-amino-5-chlorouracil	inhibits angiogenic activity, competitive	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
55000	-	SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0034	-	6-amino-5-chlorouracil	-	Homo sapiens

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Release 2023.1 (January 2023)