Literature summary for 2.4.2.31 extracted from

Di Paola, S.; Micaroni, M.; Di Tullio, G.; Buccione, R.; Di Girolamo, M.
PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ss1 (2012), PLoS ONE, 7, e37352.

Search for more literature for 2.4.2.31

Cloned(Commentary)

Cloned (Comment)	Organism
expression Escherichia coli	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
DELTA278-322	a deletion mutant lacking the region encompassing the putative transmembrane domain (aminoacids 278-322) shows a diffuse, cytosolic localization compared with full length ARTD15	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.29	-	NAD+	37°C, pH not specified in the publication	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	-	Homo sapiens	5783	-
membrane	membranes of the nuclear envelope	Homo sapiens	16020	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
50000	-	SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q8N5Y8	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
DU-145 cell	-	Homo sapiens	-
HEK-293 cell	-	Homo sapiens	-
HeLa cell	-	Homo sapiens	-
HL-60 cell	-	Homo sapiens	-
OVCAR-3 cell	-	Homo sapiens	-
SKOV-3 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
karyopherin-beta1 + NAD+	-	Homo sapiens	nicotinamide + ?	-	?

Subunits

Subunits	Comment	Organism
?	x * 50000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
ARTD15	-	Homo sapiens
PARP16/ARTD15	-	Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Homo sapiens

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Release 2023.1 (January 2023)