Literature summary for 2.4.2.31 extracted from

Hara, N.; Badruzzaman, M.; Sugae, T.; Shimoyama, M.; Tsuchiya, M.
Mouse Rt6.1 is a thiol-dependent arginine-specific ADP-ribosyltransferase cysteine 201 confers thiol sensitivity on the enzyme (1999), Eur. J. Biochem., 259, 289-294.

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Activating Compound

Activating Compound	Comment	Organism	Structure
dithiothreitol	activity of RT6.1 increases fivefold, no effect on activity of RT6.2. Cys201 confers thiol sensitivity	Mus musculus

Cloned(Commentary)

Cloned (Comment)	Organism
-	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
C201F	mutant enzyme of RT6.1, mutant enzyme loses thiol-dependency	Mus musculus
C80S	mutant enzyme of RT6.1 remains thiol-dependent	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
NEM	inhibition of RT6.1, no affect on Rt6.2 and Glu207 mutant of RR6.1	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	anchored to membranes by glycosylphosphatidylinositol	Mus musculus	16020	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
splenocyte	from BALB/c mouse	Mus musculus	-

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Release 2023.1 (January 2023)