Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | required by AT1 transferase, activates AT2 transferase | Gallus gallus |
Cloned (Comment) | Organism |
---|---|
in COS 7 cells transiently transfected with AT1 cDNA activity is detected in the culture medium. In COS 7 cells transfected with AT2 CDNA activity is found in both culture medium and cell lysate | Gallus gallus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NaCl | inhibits AT1 transferase | Gallus gallus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
NaCl | activates AT2 transferase | Gallus gallus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
x * 32000, AT1 transferase, SDS-PAGE | Gallus gallus |
34000 | - |
x * 34000, AT2 transferase, SDS-PAGE | Gallus gallus |
35318 | - |
x * 35318, AT1 transferase, calculation from nucleotide sequence | Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
2 enzyme forms: AT1 and AT2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow | - |
Gallus gallus | - |
erythrocyte | very low activity | Gallus gallus | - |
heart | low activity | Gallus gallus | - |
leukocyte | high activity | Gallus gallus | - |
liver | - |
Gallus gallus | - |
lung | - |
Gallus gallus | - |
skeletal muscle | low activity | Gallus gallus | - |
spleen | - |
Gallus gallus | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 35318, AT1 transferase, calculation from nucleotide sequence | Gallus gallus |
? | x * 34000, AT2 transferase, SDS-PAGE | Gallus gallus |
? | x * 32000, AT1 transferase, SDS-PAGE | Gallus gallus |