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Literature summary for 2.4.2.30 extracted from

  • Nicolae, C.M.; Aho, E.R.; Vlahos, A.H.; Choe, K.N.; De, S.; Karras, G.I.; Moldovan, G.L.
    The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance (2014), J. Biol. Chem., 289, 13627-13637.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens Q53GL7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
Homo sapiens
-
HeLa cell
-
Homo sapiens
-
U2OS cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
ADP-ribosyltransferase
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Homo sapiens
ARTD10
-
Homo sapiens
PARP10
-
Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme knockdown results in genomic instability and DNA damage hypersensitivity Homo sapiens
physiological function enzyme binding to proliferating cell nuclear antigen is required for translesion DNA synthesis. The enzyme is required for genomic stability, DNA damage tolerance and mutagenesis Homo sapiens