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Literature summary for 2.4.2.30 extracted from
- Characterization of Pseudomonas aeruginosa exoenzyme S as a bifunctional enzyme in J774A.1 macrophages (2003), Infect. Immun., 71, 5296-5305.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + (ADP-D-ribosyl)n-RalA | Pseudomonas aeruginosa | ADP-ribosylation of RalA by ExoS interferes with RalA activation and binding to its downstream effector in J774A.1 macrophages and suggests the potential of ExoS ADPRT activity to interfere with filiopodium formation through the inactivation of RalA and downstream effects mediated through the exocyst complex | nicotinamide + (ADP-D-ribosyl)n+1-RalA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + (ADP-D-ribosyl)n-RalA | - |
Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-RalA | - |
? | |
| NAD+ + (ADP-D-ribosyl)n-RalA | ADP-ribosylation of RalA by ExoS interferes with RalA activation and binding to its downstream effector in J774A.1 macrophages and suggests the potential of ExoS ADPRT activity to interfere with filiopodium formation through the inactivation of RalA and downstream effects mediated through the exocyst complex | Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-RalA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ADPRT | - |
Pseudomonas aeruginosa |
| exoenzyme S | - |
Pseudomonas aeruginosa |
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