Cloned (Comment) | Organism |
---|---|
- |
Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-benzylacyclouridine | 0.01 mM, 90% inhibition of normal tissues, 40-60% inhibition of carcinoma tissue | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasmic membrane | - |
Homo sapiens | - |
- |
cytoskeleton | associated with intermediate filament vimentin in fibroblasts and colon 26 cells | Mus musculus | 5856 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
4 * 33000 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
NIH 3T3 | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
uridine + phosphate = uracil + alpha-D-ribose 1-phosphate | ordered bi-bi mechanism, phosphate binds before uridine and alpha-D-ribose 1-phosphate is released after uracil | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Mus musculus | - |
additional information | present in all human tissue and tumors | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thymidine + phosphate | to a lesser extent compared to uridine | Mus musculus | thymine + 2-deoxy-alpha-D-ribose 1-phosphate | - |
? | |
thymidine + phosphate | to a lesser extent compared to uridine | Homo sapiens | thymine + 2-deoxy-alpha-D-ribose 1-phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 33000 | Homo sapiens |