Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.2.28 extracted from

  • Tang, B.; Li, Y.N.; Kruger, W.D.
    Defects in methylthioadenosine phosphorylase are associated with but not responsible for methionine-dependent tumor cell growth (2000), Cancer Res., 60, 5543-5547.
    View publication on PubMed
Search for more literature for 2.4.2.28

Cloned(Commentary)

Cloned (Comment) Organism
functional expression in enzyme deficient cell line MCF-7 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5'-methylthioadenosine + phosphate Homo sapiens
-
 adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
additional information Homo sapiens enzyme is involved in the methionine dependent tumor cell growth ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-
J-82 cell tumor-derived cell line, bladder carcinoma Homo sapiens
-
additional information enzyme defect is associated with but not responsible for methionine-dependent tumor cell growth Homo sapiens
-
MRC-5 cell lung fibroblast cell line Homo sapiens
-
RAJI cell tumor-derived cell line, Burkitt's lymphoma Homo sapiens
-
SK-N-SH cell tumor-derived cell line, neuroblastoma Homo sapiens
-
skin fibroblast cell line FC1010 skin fibroblast cell line Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-methylthioadenosine + phosphate
-
 Homo sapiens adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?
additional information enzyme is involved in the methionine dependent tumor cell growth Homo sapiens ?
-
 ?