Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.2.26 extracted from

  • Götting, C.; Kuhn, J.; Tinneberg, H.R.; Brinkmann, T.; Kleesiek, K.
    High xylosyltransferase activities in human follicular fluid and cultured granulosa-lutein cells (2002), Mol. Hum. Reprod., 8, 1079-1086.
    View publication on PubMed
Search for more literature for 2.4.2.26

Inhibitors

Inhibitors Comment Organism Structure
Glycosaminoglycans associate with the enzyme Homo sapiens
heparin
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular in cell culture supernatant Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-xylose + [protein]-L-serine Homo sapiens enzyme may play a role in maintaining the haemostatic potential of the follicular fluid UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine Homo sapiens enzyme is associated with large chondroitin sulfate-containing proteoglycans UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine Homo sapiens enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
from cell culture supernatant Homo sapiens
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
EFO-27 cell low activity Homo sapiens
-
granulosa cell cell culture Homo sapiens
-
HeLa cell low activity Homo sapiens
-
JAR cell
-
 Homo sapiens
-
additional information no activity in EFO-21 cells Homo sapiens
-
ovarian follicle mainly produced by granulosa-lutein cells Homo sapiens
-
ovarian follicle follicular fluid Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine enzyme may play a role in maintaining the haemostatic potential of the follicular fluid Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine enzyme is associated with large chondroitin sulfate-containing proteoglycans Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-D-xylose + bikunin recombinant mutant bikunin Homo sapiens UDP + D-xylosyl-bikunin bound to serine residue ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
 assay at Homo sapiens