Any feedback?
Literature summary for 2.4.2.18 extracted from
- Mutations in the trpD gene of Corynebacterium glutamicum confer 5-methyltryptophan resistance by encoding a feedback-resistant anthranilate phosphoribosyltransferase (1995), Appl. Environ. Microbiol., 61, 4477-4479.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Corynebacterium glutamicum |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5-Methyltryptophan | 0.32 mM | Corynebacterium glutamicum |  |
| L-tryptophan | 0.83 mM | Corynebacterium glutamicum | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | Corynebacterium glutamicum | enzyme of tryptophan biosynthesis | N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Corynebacterium glutamicum | - |
wild-type and 5-methyltryptophan resistant mutant | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.049 | - |
wild-type, crude extract | Corynebacterium glutamicum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Corynebacterium glutamicum | N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | - |
? | |
| anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | enzyme of tryptophan biosynthesis | Corynebacterium glutamicum | N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
