Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli M15[pREP4]cells | Plasmodium falciparum |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
2 * 33000, SDS-PAGE. Orotate phosphoribosyltransferase and orotidine 5-monophosphate decarboxylase exist physically as a heterotetrameric enzyme complex containing two subunits of each enzyme | Plasmodium falciparum |
67000 | - |
gel filtration | Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | Plasmodium falciparum | - |
orotidine 5'-phosphate + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | Q8N0R1 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography | Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Plasmodium falciparum | orotidine 5'-phosphate + diphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 33000, SDS-PAGE. Orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase exist physically as a heterotetrameric enzyme complex containing two subunits of each enzyme | Plasmodium falciparum |
Synonyms | Comment | Organism |
---|---|---|
OPRT | - |
Plasmodium falciparum |