Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
nucleus | in metastatic lymph nodes and lymphovascularly invasive lesions | Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelium | in normal non-neoplastic colorectal epithelium, granular staining is observed only in the crypt | Homo sapiens | - |
additional information | in mucosal carcinoma lesions frequency of OPRT expression is 32.1%, in infiltrative lesions frequency of OPRT expression is 69.8%. In lymphovascularly invasive lesions frequency of OPRT expression is 88.2% and in metastatic lymph nodes frequency of OPRT expression is 88.8% | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
OPRT | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | non-cancerous components do not express OPRT | down |
Homo sapiens | lexpression of OPRT in mucosal carcinoma components, in infiltrative components, in lymphovascularly invasive lesions and in metastatic lymph nodes. No significant correlation between OPRT expression and cancer stage, T-grade or N-grade, but OPRT expression correlates positively with the presence of lymphovascular invasion. OPRT is diffusely expressed to a greater extent, especially in the tumor cells adjacent to the infiltrative margin | up |