Literature summary for 2.4.2.1 extracted from

Nunez, S.; Wing, C.; Antoniou, D.; Schramm, V.L.; Schwartz, S.D.
Insight into catalytically relevant correlated motions in human purine nucleoside phosphorylase (2006), J. Phys. Chem. A, 110, 463-472.

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Protein Variants

Protein Variants	Comment	Organism
F159G	mutant displays a strong increase in KM and modest decrease in kcat	Homo sapiens
F200G	mutant displays a strong increase in KM and modest decrease in kcat	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
immucillin-H	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P00491	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
guanosine + phosphate	insight into catalytically relevant correlated motions in human purine nucleoside phosphorylase	Homo sapiens	guanine + alpha-D-ribose 1-phosphate	-	?

Synonyms

Synonyms	Comment	Organism
hPNP	-	Homo sapiens

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Release 2023.1 (January 2023)