Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-D-ribose 1-phosphate | - |
Homo sapiens | |
guanine | - |
Homo sapiens | |
guanosine | product inhibition | Homo sapiens | |
phosphate | product inhibition | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0308 | - |
guanine | - |
Homo sapiens | |
0.039 | - |
hypoxanthine | - |
Homo sapiens | |
0.0443 | - |
guanosine | - |
Homo sapiens | |
0.0443 | - |
deoxyguanosine | - |
Homo sapiens | |
0.05 | - |
Inosine | - |
Homo sapiens | |
0.167 | - |
6-mercaptoguanosine | - |
Homo sapiens | |
0.228 | - |
alpha-D-ribose 1-phosphate | reaction with guanine | Homo sapiens | |
13.1 | - |
phosphate | reaction with guanosine | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
2 * 32000, SDS-PAGE | Homo sapiens |
67000 | - |
equilibrium sedimentation, gel filtration, amino acid analysis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
purine ribonucleoside + phosphate = purine + alpha-D-ribose 1-phosphate | Theorell-Chance mechanism | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
55 | - |
reaction with guanosine | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-mercaptoguanosine + phosphate | - |
Homo sapiens | alpha-D-ribose 1-phosphate + 6-mercaptoguanine | - |
? | |
deoxyguanosine + phosphate | - |
Homo sapiens | guanine + alpha-D-deoxyribose 1-phosphate | - |
? | |
guanosine + phosphate | - |
Homo sapiens | guanine + alpha-D-ribose 1-phosphate | - |
r | |
inosine + phosphate | - |
Homo sapiens | hypoxanthine + alpha-D-ribose 1-phosphate | - |
r |
Subunits | Comment | Organism |
---|---|---|
monomer | 2 * 32000, SDS-PAGE | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | - |
guanosine | with guanine as variable substrate and ribose 1-phosphate as fixed substrate | Homo sapiens | |
0.0125 | - |
guanine | with guanosine as variable substrate and phosphate as fixed substrate | Homo sapiens |