Literature summary for 2.4.1.B65 extracted from

Velickovic, D.; Dimitrijevic, A.; Bihelovic, F.; Bezbradica, D.; Knezevic-Jugovic, Z.; Milosavic, N.
Novel glycoside of vanillyl alcohol, 4-hydroxy-3-methoxybenzyl-alpha-D-glucopyranoside: study of enzymatic synthesis, in vitro digestion and antioxidant activity (2012), Bioprocess Biosyst. Eng., 35, 1107-1115.

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Application

Application	Comment	Organism
medicine	reaction product vanillyl alcohol alpha-D-glucoside shows good antioxidant activity as well as stability in gastrointestinal tract. It is hydrolyzed on brush border membrane of enterocytes, so it can serve in protecting the gastrointestinal system from oxidation	Saccharomyces cerevisiae
synthesis	at optimum reaction temperature of 37°C, optimal maltose concentration of 60% (w/v), optimal pH 6.6, and optimal concentration of vanillyl alcohol of 158 mM, yield of vanillyl alcohol alpha-D-glucoside is 90 mM with no by product formation. This compound shows good antioxidant activity as well as stability in gastrointestinal tract. It is hydrolyzed on brush border membrane of enterocytes, so it can serve in protecting the gastrointestinal system from oxidation	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P53341	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
vanillyl alcohol + maltose	-	Saccharomyces cerevisiae	4-hydroxy-3-methoxybenzyl alpha-D-glucopyranoside + D-glucose	-	?
vanillyl alcohol + maltose	-	Saccharomyces cerevisiae	vanillyl alcohol alpha-D-glucoside + D-glucose	-	?

Synonyms

Synonyms	Comment	Organism
maltase	-	Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	-	Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
6.6	-	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)