Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridioides difficile | - |
- |
- |
General Information | Comment | Organism |
---|---|---|
physiological function | toxin A, toxin B or crude toxin preparations have no effect on membrane integrity of either intestinal cells or McCoy cells as judged by nucleotide leakage. Toxins A and B, on their own ortogether in crude preparations, have no effect on the rate of protein synthesis in isolated intestinal cells in vitro. Both toxins inhibit protein synthesis in McCoy cells, and inhibition of protein synthesis could be a causative factor in the development of cytopathic effects | Clostridioides difficile |