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Literature summary for 2.4.1.92 extracted from

  • Song, N.; Kim, S.J.; Kwon, H.Y.; Son, S.W.; Kim, K.S.; Ahn, H.B.; Lee, Y.C.
    Transcriptional activation of human GM3 synthase (hST3Gal V) gene by valproic acid in ARPE-19 human retinal pigment epithelial cells (2011), BMB Rep., 44, 405-409.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
ARPE-19 cell
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Homo sapiens
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retinal pigment epithelial cell
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Homo sapiens
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Synonyms

Synonyms Comment Organism
GM3 synthase
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Homo sapiens
ST3Gal V
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the transcriptional activity of GM3 synthase induced by valproic acid (2.4fold by 1 mM) in ARPE-19 cells is inhibited by SP600125. ATF2 binding to the CREB/ATF binding site at -143 is essential for transcriptional activation of the enzyme in valproic acid-induced ARPE-19 cells up