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Literature summary for 2.4.1.92 extracted from

  • Gotoh, M.; Sato, T.; Kiyohara, K.; Kameyama, A.; Kikuchi, N.; Kwon, Y.D.; Ishizuka, Y.; Iwai, T.; Nakanishi, H.; Narimatsu, H.
    Molecular cloning and characterization of beta1,4-N-acetylgalactosaminyltransferases IV synthesizing N,N'-diacetyllactosediamine (2004), FEBS Lett., 562, 134-140.
    View publication on PubMed
Search for more literature for 2.4.1.92

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q76KP1
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information protein has 3 potential N-gylcosylation sites and a DXH-sequence Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain adult and fetal Homo sapiens
-
kidney fetal Homo sapiens
-
lung fetal Homo sapiens
-
ovary
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme shows similar specificities for O-and N-glykans. Efficiency of transfer decreases as the number of antennas increases Homo sapiens ?
-
 ?
UDP-N-acetylgalactosamine + GlcNAcbeta(1-3)GalNAcalpha-p-nitrophenol (core 3-p-nitrophenol) 20% of activity compared with N-acetylglucosamine-beta-benzyl Homo sapiens UDP + GalNAcbeta(1-4)GlcNAcbeta(1-3)GalNAcalpha-p-nitrophenol
-
 ?
UDP-N-acetylgalactosamine + GlcNAcbeta(1-6)(Galbeta1-3)GalNAcalpha-p-nitrophenol (core 2-p-nitrophenol) 15.2% of activity compared with N-acetylglucosamine-beta-benzyl Homo sapiens UDP + GalNAcbeta(1-4)GlcNAcbeta(1-6)(Galbeta1-3)GalNAcalpha-p-nitrophenol
-
 ?
UDP-N-acetylgalactosamine + GlcNAcbeta(1-6)GalNAcalpha-p-nitrophenol (core 6-p-nitrophenol) 190.7% of activity compared with N-acetylglucosamine-beta-benzyl Homo sapiens UDP + GalNAcbeta(1-4)GlcNAcbeta(1-6)GalNAcalpha-p-nitrophenol
-
 ?
UDP-N-acetylgalactosamine + N-acetylglucosamine-beta-benzyl
-
 Homo sapiens N,N'-diacetyllactosediamine + benzol formation of beta-1,4-linkage ?

Subunits

Subunits Comment Organism
More type II transmembrane protein Homo sapiens

Synonyms

Synonyms Comment Organism
betaGalNAc-T4
-
 Homo sapiens