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Literature summary for 2.4.1.87 extracted from

  • Taylor, S.G.; McKenzie, I.F.; Sandrin, M.S.
    Characterization of the rat alpha(1,3)galactosyltransferase: evidence for two independent genes encoding glycosyltransferases that synthesize Galalpha(1,3)Gal by two separate glycosylation pathways (2003), Glycobiology, 13, 327-337.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
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 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactose + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R Rattus norvegicus alpha(1,3)GT is able to synthesize Galalpha(1,3)Gal on glycoproteins destined for the cell surface. Igb3S shows no activity with glycoproteins but is capable of synthesizing Galalpha(1,3)Gal on glycolipids UDP + alpha-D-galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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 alpha(1,3)GT
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Rattus norvegicus
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 iGb3 synthase
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Source Tissue

Source Tissue Comment Organism Textmining
brain
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 Rattus norvegicus
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heart
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 Rattus norvegicus
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kidney
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 Rattus norvegicus
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liver
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 Rattus norvegicus
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spleen
-
 Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R alpha(1,3)GT is able to synthesize Galalpha(1,3)Gal on glycoproteins destined for the cell surface. Igb3S shows no activity with glycoproteins but is capable of synthesizing Galalpha(1,3)Gal on glycolipids Rattus norvegicus UDP + alpha-D-galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R
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 ?

Synonyms

Synonyms Comment Organism
alpha(1,3)GT two independent genes encode glycosyltransferases that synthesize Galalpha(1,3)Gal by two separate glycosylation pathways, alpha(1,3)GT and iGb3 synthase Rattus norvegicus
iGb3 synthase two independent genes encode glycosyltransferases that synthesize Galalpha(1,3)Gal by two separate glycosylation pathways, alpha(1,3)GT and iGb3 synthase Rattus norvegicus