Literature summary for 2.4.1.86 extracted from

Basu, M.; Presper, K.A.; Basu, S.; Hoffmann, L.M.; Brooks, S.E.
Differential activities of glycolipid glycosyltransferases in Tay-Sachs disease: studies in cultured cells from cerebrum (1979), Proc. Natl. Acad. Sci. USA, 76, 4270-4274.

Search for more literature for 2.4.1.86

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
UDPgalactose + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide	Homo sapiens	enzyme is involved in the synthesis in vitro of gangliosides and blood group-related glycosphingolipids	UDP + 1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	fetus with Tay-Sachs disease	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
Tay-Sachs disease specific cell type	SV40-transformed glial cell culture derived from the cerebrum of a human fetus with Tay-Sachs disease specific cell type	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDPgalactose + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide	-	Homo sapiens	UDP + 1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide	-	?
UDPgalactose + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide	enzyme is involved in the synthesis in vitro of gangliosides and blood group-related glycosphingolipids	Homo sapiens	UDP + 1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)