Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.83 extracted from

  • Zhang, Z.; Banerjee, A.; Baksi, K.; Banerjee, D.
    Mannosylphosphodolichol synthase overexpression supports angiogenesis (2010), Biocatal. Biotransform., 28, 90-98.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.83

Cloned(Commentary)

Cloned (Comment) Organism
capillary endothelial cell clone overexpressing the gene encoding DPMS synthetic construct

Organism

Organism UniProt Comment Textmining
synthetic construct
-
-
-

Synonyms

Synonyms Comment Organism
DPMS
-
 synthetic construct
mannosylphosphodolichol synthase
-
 synthetic construct

Expression

Organism Comment Expression
synthetic construct the DPMS-overexpressing clone has a high level of DPMS mRNA, expresses nearly 4times more DPMS protein than the clone transfected with pEGFP-N1 vector only and has 108% higher DPMS activity than the vector control up

General Information

General Information Comment Organism
physiological function high level of expression of (GlcNAc-beta-(1,4)-GlcNAc) 1-4-beta-GlcNAc-NeuAc glycans on the external surface of the capillary endothelial cells overexpressing DPMS. Increased cellular proliferation and accelerated healing of the wound induced by mechanical stress of the DPMS-overexpressing clone unequivocally supports a role of DPMS in angiogenesis synthetic construct