Cloned (Comment) | Organism |
---|---|
overexpression in cancer cell lines selected for resistance to natural product chemotherapy, i.e. cell lines KB-3-1, KB-V.01, KB-V.1, KB-V1, KB-A.05, MCF-7, and MCF-7-AdrR, cell lines show different recombinant enzyme activity, which is higherin cells resistant to natural product anticancer agents, e.g. vinblastine and adriamycin, overview | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00017 | - |
recombinant enzyme in cell extract of cell line KB-3-1 | Homo sapiens |
0.00021 | - |
recombinant enzyme in cell extract of cell line KB-A1 | Homo sapiens |
0.00024 | - |
recombinant enzyme in cell extract of cell line KB-V.1 | Homo sapiens |
0.00025 | - |
recombinant enzyme in cell extract of cell line KB-A.05 | Homo sapiens |
0.00036 | - |
recombinant enzyme in cell extract of cell line KB-V1 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-glucose + C6-ceramide | - |
Homo sapiens | UDP + glucosyl-C6-ceramide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glucosylceramide synthase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
assay at | Homo sapiens |