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Literature summary for 2.4.1.79 extracted from

  • Chien, J.L.; Williams, T.; Basu, S.
    Biosynthesis of a globoside-type glycosphingolipid by a beta-N-acetylgalactosaminyltransferase from embryonic chicken brain (1973), J. Biol. Chem., 248, 1778-1785.
    View publication on PubMed
Search for more literature for 2.4.1.79

Activating Compound

Activating Compound Comment Organism Structure
Myrj 59 activation is half as effective as with taurocholate Gallus gallus
nonionic detergents activation, e.g. Triton X-100 or CF-54 Gallus gallus
sodium taurocholate required for optimal activity Gallus gallus
Tween 20 activation is half as effective as with taurocholate Gallus gallus

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Gallus gallus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.2
-
 UDP-N-acetylgalactosamine
-
 Gallus gallus
1.7
-
 D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
-
 Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane bound to Gallus gallus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ 46% of the activation with Mn2+ Gallus gallus
Mn2+ required Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
 embryo
-

Source Tissue

Source Tissue Comment Organism Textmining
brain embryonic Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-galactosamine + D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
-
 Gallus gallus UDP + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
 Gallus gallus