Literature summary for 2.4.1.69 extracted from

Moehler, T.M.; Sauer, S.; Witzel, M.; Andrulis, M.; Garcia-Vallejo, J.J.; Grobholz, R.; Willhauck-Fleckenstein, M.; Greiner, A.; Goldschmidt, H.; Schwartz-Albiez, R.
Involvement of alpha 1-2-fucosyltransferase I (FUT1) and surface-expressed Lewis(y) (CD174) in first endothelial cell-cell contacts during angiogenesis (2008), J. Cell. Physiol., 215, 27-36.

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Application

Application	Comment	Organism
medicine	involvement of alpha 1-2-fucosyltransferase I (FUT1) and surface-expressed Lewis(y) (CD174) in first endothelial cell-cell contacts during angiogenesis is shown	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	human bone marrow endothelial cells (HBMEC) FUT1-siRNA-transfectants display impaired in vitro angiogenesis when cultivated on extracellular matrix and in spheroid assays	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
human bone marrow endothelial cell line	an enhanced expression of CD173/CD174 and transcription of FUT1 is observed after treatment of human bone marrow endothelial cells (HBMEC) with tumor necrosis factor-alpha (TNF-alpha) or conditioned supernatants of the leukemia cell line KG1a	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
alpha(1,2)fucosyltransferase I	-	Homo sapiens
FUT1	-	Homo sapiens

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Release 2023.1 (January 2023)