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Literature summary for 2.4.1.68 extracted from
- Chemical modifications of alpha1,6-fucosyltransferase define amino acid residues of catalytic importance (2003), Biochimie, 85, 303-310.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diethyl dicarbonate | 10 mM, about 90% inhibition | Homo sapiens |  |
| GDP | - |
Homo sapiens | |
| GMP | - |
Homo sapiens | |
| GTP | - |
Homo sapiens | |
| iodoacetamide | 10 mM, about 50% inhibition | Homo sapiens | |
| iodoacetic acid | 10 mM, 35% inhibition | Homo sapiens | |
| Mersalyl | 5 mM, complete inhibition, inhibition can be very significantly prevented by GDP-fucose, GDP or GnGnGp | Homo sapiens | |
| methyl iodide | 1 mM, about 70% inhibition | Homo sapiens | |
| PCMB | 5 mM, complete inhibition, inhibition can be very significantly prevented by GDP-fucose, GDP or GnGnGp | Homo sapiens | |
| Phenylglyoxal | 10 mM, 90% inhibition | Homo sapiens | |
| pyridoxal 5'-phosphate | 10 mM, about 85% inhibition | Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.03 | - |
GDP-L-fucose | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood platelet | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha6FucT | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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