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Literature summary for 2.4.1.66 extracted from

  • Wang, C.; Kovanen, V.; Raudasoja, P.; Eskelinen, S.; Pospiech, H.; Myllylae, R.
    The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability (2009), J. Cell. Mol. Med., 13, 508-521.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.66

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in HT-1080 cells, expression of fragments in Escherichia coli Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information LH-deficient mutant, deficiency of LH3 glycosyltransferase activity decreases cell growth and increases lethality Homo sapiens
additional information overexpression of LH3, increased hydroxylation of lysyl residues and increased galactosylation and glucosylation of hydroxylysyl residues Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
85000
-
 SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O60568
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA-agarose Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
CCD-19LU cell
-
 Homo sapiens
-
embryonic kidney cell line
-
 Homo sapiens
-
fibrosarcoma cell line
-
 Homo sapiens
-
HEK-293 cell
-
 Homo sapiens
-
HT-1080 cell
-
 Homo sapiens
-
lung fibroblast cell line
-
 Homo sapiens
-
MG-63 cell
-
 Homo sapiens
-
osteosarcoma cell
-
 Homo sapiens
-